Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909957 | 0.79 | KDM4E (0.41) | PI4KBPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL23909969 | 0.76 | PIK3CG (0.43) | LRRK2PI4KBPIK3CDPIK3CBPI4KA | |
| SCHEMBL23910057 | 0.76 | KDM4E (0.44) | PIK3CDMAP4K4ALOX5APFEN1KDM4E | |
| SCHEMBL20329653 | 0.76 | KDM4E (0.49) | PI4KBPIK3CDPIP5K1CPIK3CBPI4KA | |
| SCHEMBL23909947 | 0.76 | KDM1A (0.43) | KDM1AALOX5APFEN1KDM4EUSP2 | |
| SCHEMBL20329654 | 0.74 | PIK3CD (0.43) | PI4KBPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL23910065 | 0.74 | ALOX5AP (0.41) | PI4KBMAP4K4MINK1ALOX5APFEN1 | |
| SCHEMBL23910121 | 0.73 | ALOX5AP (0.41) | PIK3CDMAP4K4ALOX5APFEN1KDM4E | |
| SCHEMBL21071606 | 0.73 | ALOX5AP (0.46) | PI4KBPIK3CDPIK3CBPI4KAPIK3CG | |
| SCHEMBL30101062 | 0.73 | KDM4E (0.48) | ALOX5APFEN1STSKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | LRRK2 4268/4885PI4KB 3755/4885PIK3CD 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.