Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909979 | 0.81 | AAK1 (0.44) | ALOX5APFEN1KDM4ELMNACYP11B2 | |
| SCHEMBL23909957 | 0.78 | KDM4E (0.41) | ALOX5APFEN1KDM4EALDH1A1USP2 | |
| SCHEMBL26926454 | 0.78 | VCAM1 (0.45) | ALOX5APFEN1KDM4ELMNAALDH1A1 | |
| SCHEMBL21071606 | 0.78 | ALOX5AP (0.46) | ALOX5APFEN1PIK3CDMAP4K4 | |
| SCHEMBL23910065 | 0.76 | ALOX5AP (0.41) | ALOX5APFEN1KDM4ECYP11B2CYP11B1 | |
| SCHEMBL20329653 | 0.75 | KDM4E (0.49) | KDM4EALDH1A1USP2PIK3CD | |
| SCHEMBL23909947 | 0.75 | KDM1A (0.43) | ALOX5APFEN1KDM4ECYP11B2CYP11B1 | |
| SCHEMBL30101062 | 0.75 | KDM4E (0.48) | ALOX5APFEN1KDM4ELMNACYP11B2 | |
| SCHEMBL23910057 | 0.75 | KDM4E (0.44) | ALOX5APFEN1KDM4ELMNACYP11B2 | |
| SCHEMBL20329860 | 0.75 | PIK3CA (0.44) | ALOX5APFEN1KDM4ECYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | ALOX5AP 419/4885FEN1 4761/4885KDM4E 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.