Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.41 |
| ▸ | FEN1 | P39748 | 5/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | GCKR | Q14397 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071606 | 0.89 | ALOX5AP (0.46) | ALOX5APFEN1MAP4K4PIK3CAKCNH2 | |
| SCHEMBL23915999 | 0.86 | ALOX5AP (0.39) | ALOX5APFEN1MAP4K4PIK3CAKCNH2 | |
| SCHEMBL23909957 | 0.79 | KDM4E (0.41) | ALOX5APFEN1PIK3CAPI4KBKDM4E | |
| SCHEMBL23910112 | 0.78 | ALOX5AP (0.44) | ALOX5APFEN1GABRA1GABRG2GABRB3 | |
| SCHEMBL23910057 | 0.76 | KDM4E (0.44) | ALOX5APFEN1MAP4K4KDM4EUSP2 | |
| SCHEMBL23910121 | 0.76 | ALOX5AP (0.41) | ALOX5APFEN1MAP4K4KDM4EUSP2 | |
| SCHEMBL20329653 | 0.76 | KDM4E (0.49) | PIK3CAKCNH2PI4KBKDM4EUSP2 | |
| SCHEMBL23909947 | 0.76 | KDM1A (0.43) | ALOX5APFEN1KDM4EUSP2ALDH1A1 | |
| SCHEMBL23910053 | 0.74 | LRRK2 (0.47) | ALOX5APFEN1MAP4K4PIK3CAKCNH2 | |
| SCHEMBL20329654 | 0.74 | PIK3CD (0.43) | PIK3CAPI4KBGABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | ALOX5AP 419/4885FEN1 4761/4885MAP4K4 2906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.