Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071766 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNAVCAM1BCHEGAA | |
| SCHEMBL23910013 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNAVCAM1BCHEGAA | |
| SCHEMBL23909986 | 0.81 | LMNA (0.52) | ALDH1A1LMNAVCAM1BCHEGAA | |
| SCHEMBL21071846 | 0.81 | LMNA (0.51) | ALDH1A1LMNAVCAM1BCHEGAA | |
| SCHEMBL23910092 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNAVCAM1BCHEGAA | |
| SCHEMBL23909943 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNAVCAM1BCHEGAA | |
| SCHEMBL15331880 | 0.78 | ALDH1A1 (0.49) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL23910035 | 0.77 | KDM4E (0.49) | ALDH1A1LMNAGAAMAPTMEN1 | |
| SCHEMBL3156146 | 0.76 | LMNA (0.57) | ALDH1A1LMNAVCAM1BCHEGAA | |
| SCHEMBL19814271 | 0.75 | ALDH1A1 (0.62) | ALDH1A1LMNAVCAM1BCHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | ALDH1A1 485/4885LMNA 2967/4885VCAM1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.