Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 3/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183458 | 0.82 | WNT3A (0.47) | WNT3AAAK1DYRK1AGSK3BKDM4E | |
| SCHEMBL12302782 | 0.82 | WNT3A (0.43) | ADORA2BWNT3AALOX5APFEN1AAK1 | |
| SCHEMBL23910018 | 0.81 | CYP3A4 (0.47) | ALOX5APFEN1AAK1PARP10PARP11 | |
| SCHEMBL23909979 | 0.81 | AAK1 (0.44) | ALOX5APFEN1AAK1DYRK1AGSK3B | |
| SCHEMBL23212160 | 0.80 | ALOX5AP (0.49) | WNT3AALOX5APFEN1DYRK1AGSK3B | |
| SCHEMBL8111393 | 0.79 | KDM4E (0.45) | GSK3BKDM4EALDH1A1USP2MAPT | |
| SCHEMBL20329372 | 0.78 | MTOR (0.45) | WNT3AALOX5APFEN1AAK1DYRK1A | |
| SCHEMBL20329371 | 0.78 | AAK1 (0.49) | AAK1DYRK1AGSK3BKDM4EALDH1A1 | |
| SCHEMBL23012421 | 0.78 | ADORA2B (0.43) | ADORA2BWNT3AALOX5APFEN1AAK1 | |
| SCHEMBL29691432 | 0.78 | ADORA2B (0.43) | ADORA2BWNT3AALOX5APFEN1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | ADORA2B 1323/4885WNT3A 2879/4885ALOX5AP 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.