SCHEMBL23911753

SCHEMBL23911753

c1ccc(-c2nnc(-c3ccccc3)n2-c2cccc3c4ccccc4n(-c4ccccc4-c4ccccc4-n4c5ccccc5c5ccc6c7ccccc7oc6c54)c23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 2/20 0.38
ALOX5 P09917 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD11B1 P28845 1/20 0.33
PRKDC P78527 2/20 0.33
DUSP3 P51452 1/20 0.32
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
CSF1R P07333 1/20 0.31
PDGFRB P09619 1/20 0.31
KIT P10721 1/20 0.31
FLT3 P36888 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
GGPS1 O95749 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21532321 0.94 SMN1; SMN2 (0.36) AKT1ALOX5SMN1; SMN2HIF1AMEN1
SCHEMBL21532549 0.92 AKT1 (0.35) AKT1ALOX5SMN1; SMN2HIF1AHSD11B1
SCHEMBL21532258 0.91 ALOX5 (0.35) AKT1ALOX5SMN1; SMN2HIF1APRKDC
SCHEMBL21532466 0.91 AKT1 (0.34) AKT1ALOX5SMN1; SMN2HIF1AHSD11B1
SCHEMBL21532544 0.91 KDM4E (0.36) AKT1ALOX5SMN1; SMN2HSD11B1PRKDC
SCHEMBL21532522 0.90 AKT1 (0.34) AKT1ALOX5SMN1; SMN2HIF1AHSD11B1
SCHEMBL21532713 0.89 OPRD1 (0.34) AKT1ALOX5SMN1; SMN2HIF1AMEN1
SCHEMBL21532539 0.88 ALDH1A1 (0.35) AKT1ALOX5SMN1; SMN2PRKDCMAPT
SCHEMBL21532619 0.87 KDM4E (0.37) AKT1ALOX5SMN1; SMN2HSD11B1PRKDC
SCHEMBL21532780 0.87 AKT1 (0.38) AKT1SMN1; SMN2HIF1AHSD11B1DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11145825-B2 Condensed cyclic compound and organic light-emitting device including i he same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145825-B2 Condensed cyclic compound and organic light-emitting device including i he same CRY1, CCNT1, CCNA1 AKT1 2105/4885ALOX5 3170/4885SMN1; SMN2 2430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.