Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642427 | 0.77 | HPGD (0.35) | DDB1CRBNMEN1KMT2AGAA | |
| SCHEMBL22591718 | 0.72 | MEN1 (0.65) | SMN1; SMN2KLK5MEN1CYP1A2KMT2A | |
| SCHEMBL22591724 | 0.72 | MEN1 (0.65) | SMN1; SMN2KLK5MEN1CYP1A2KMT2A | |
| SCHEMBL6887643 | 0.71 | PSEN1 (0.39) | ALDH1A1 | |
| SCHEMBL25226256 | 0.71 | ALDH1A1 (0.53) | SMN1; SMN2KLK5MEN1CYP1A2KMT2A | |
| SCHEMBL23911983 | 0.67 | PTGIR (0.35) | DDB1CRBNKMT2AALDH1A1 | |
| SCHEMBL22591709 | 0.66 | MEN1 (0.59) | SMN1; SMN2KLK5MEN1CYP1A2KMT2A | |
| SCHEMBL23642642 | 0.66 | MEN1 (0.59) | SMN1; SMN2KLK5MEN1CYP1A2KMT2A | |
| SCHEMBL14856205 | 0.65 | ALDH1A1 (0.62) | CRBNALDH1A1KDM4E | |
| SCHEMBL14856743 | 0.65 | ALDH1A1 (0.62) | CRBNALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601263-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-10-13 | — | — | EP | disclosed |