Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 2/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912017 | 0.80 | RBP4 (0.38) | KMT2AMEN1LMNA | |
| SCHEMBL23911983 | 0.77 | PTGIR (0.35) | PTGIRDDB1CRBNKMT2ALMNA | |
| SCHEMBL23911957 | 0.77 | SMN1; SMN2 (0.41) | HPGDDDB1CRBNKMT2AMEN1 | |
| SCHEMBL23642631 | 0.75 | TP53 (0.49) | KMT2AMEN1LMNAGAAFPR2 | |
| SCHEMBL909447 | 0.69 | ALDH1A1 (0.38) | HPGDKMT2AMEN1LMNAGAA | |
| SCHEMBL23911988 | 0.68 | ALDH1A1 (0.47) | LMNA | |
| SCHEMBL22304658 | 0.67 | HTR2B (0.36) | KMT2AMEN1LMNA | |
| SCHEMBL23911979 | 0.66 | LMNA (0.43) | KMT2AMEN1LMNAGAA | |
| SCHEMBL23642556 | 0.65 | HRH3 (0.36) | — | |
| SCHEMBL909098 | 0.65 | NOS3 (0.33) | KMT2AMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601263-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-10-13 | — | — | EP | disclosed |
| EP-3368523-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-07-14 | — | — | EP | disclosed |