Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642644 | 0.82 | MDM2 (0.32) | DDB1CRBN | |
| SCHEMBL23642427 | 0.77 | HPGD (0.35) | PTGIRDDB1CRBNLMNAKMT2A | |
| SCHEMBL23642606 | 0.77 | TP53 (0.46) | ALDH1A1LMNAKMT2A | |
| SCHEMBL22304658 | 0.76 | HTR2B (0.36) | KIF11ALDH1A1LMNAKMT2A | |
| SCHEMBL23642424 | 0.76 | RBP4 (0.38) | — | |
| SCHEMBL23912012 | 0.74 | MGLL (0.38) | NOTUM | |
| SCHEMBL23642556 | 0.72 | HRH3 (0.36) | — | |
| SCHEMBL23642705 | 0.70 | NOTUM (0.35) | NOTUM | |
| SCHEMBL25895244 | 0.69 | — | — | |
| SCHEMBL24576664 | 0.68 | MDM2 (0.37) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601263-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-10-13 | — | — | EP | disclosed |