Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642556 | 0.82 | HRH3 (0.36) | — | |
| SCHEMBL22304657 | 0.80 | POLQ (0.37) | HTR2BHTR7GUSBKIF11LMNA | |
| SCHEMBL23911984 | 0.79 | ROCK2 (0.39) | HTR2BHTR2AHTR2CGUSBTSHR | |
| SCHEMBL23642424 | 0.78 | RBP4 (0.38) | HTR2BHTR2AHTR2CHTR7GUSB | |
| SCHEMBL23911983 | 0.76 | PTGIR (0.35) | KIF11LMNAALDH1A1KMT2A | |
| SCHEMBL25317840 | 0.75 | HTR2B (0.38) | HTR2BHTR2AHTR2CHTR7GUSB | |
| SCHEMBL27251508 | 0.72 | CCKAR (0.36) | MEN1KMT2A | |
| SCHEMBL25313489 | 0.72 | RPS6KB1 (0.38) | HTR2BHTR2AHTR2CHTR7GUSB | |
| SCHEMBL25895244 | 0.72 | — | — | |
| SCHEMBL25319499 | 0.71 | ALDH1A1 (0.40) | HTR2BHTR2AHTR2CGUSBRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160202-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2020-08-06 | — | — | WO | disclosed |