SCHEMBL23912093

SCHEMBL23912093

Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(-c3cccnc3)cc(-n3c4ccccc4c4cc(-c5ccc(C)cc5C)ccc43)c2C#N)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 5/20 0.44
TP53 P04637 2/20 0.39
NPC1 O15118 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP17A1 P05093 2/20 0.38
CYP11B1 P15538 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MAOA P21397 1/20 0.37
SQOR Q9Y6N5 1/20 0.36
SLC2A1 P11166 1/20 0.35
FLT3 P36888 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
ALDH1A1 P00352 1/20 0.35
IKBKB O14920 1/20 0.35
DHODH Q02127 1/20 0.34
PDE10A Q9Y233 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20619434 0.94 CYP11B2 (0.44) CYP11B2TP53NPC1MAPTRAB9A
SCHEMBL20620032 0.91 CYP11B2 (0.47) CYP11B2TP53NPC1RAB9ASMN1; SMN2
SCHEMBL23912088 0.90 CYP11B2 (0.41) CYP11B2TP53NPC1MAPTRAB9A
SCHEMBL23912060 0.90 CYP11B2 (0.51) CYP11B2CYP11B1TDP1MAOAKDM4E
SCHEMBL19909063 0.89 SQOR (0.34) CYP11B2TP53NPC1MAPTRAB9A
SCHEMBL20620034 0.88 CYP11B2 (0.47) CYP11B2MAPTSMN1; SMN2CYP17A1CYP11B1
SCHEMBL20620030 0.88 CYP11B2 (0.44) CYP11B2TP53NPC1RAB9ASMN1; SMN2
SCHEMBL23912059 0.86 CYP11B2 (0.51) CYP11B2CYP11B1TDP1MAOASQOR
SCHEMBL23912078 0.86 CYP11B2 (0.46) CYP11B2SMN1; SMN2CYP17A1CYP11B1TDP1
SCHEMBL19909219 0.86 ADORA2A (0.43) NPC1MAPTSMN1; SMN2TDP1SQOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645522-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-10-13 EP disclosed