Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450441 | 0.82 | P2RX7 (0.40) | ALDH1A1P2RX7CYP3A4TSHRADAM17 | |
| SCHEMBL201527 | 0.80 | P2RX7 (0.41) | ALDH1A1P2RX7TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL23912210 | 0.77 | NPC1 (0.41) | P2RX7SMN1; SMN2L3MBTL1 | |
| SCHEMBL14628487 | 0.76 | P2RX7 (0.36) | ALDH1A1P2RX7 | |
| SCHEMBL201163 | 0.76 | CYP2D6 (0.38) | ALDH1A1P2RX7 | |
| SCHEMBL4253408 | 0.76 | P2RX7 (0.36) | ALDH1A1P2RX7 | |
| SCHEMBL4103952 | 0.75 | KMT2A (0.43) | ALDH1A1P2RX7SMN1; SMN2 | |
| SCHEMBL1451060 | 0.75 | CETP (0.37) | ALDH1A1P2RX7TSHR | |
| SCHEMBL5347783 | 0.75 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL32674103 | 0.74 | ALDH1A1 (0.53) | ALDH1A1DDB1CRBNTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640255-B1 | METHOD FOR PRODUCING SILICON COMPOUND, AND SILICON COMPOUND | SHINETSU CHEMICAL CO (JP) | 2021-10-13 | — | — | EP | disclosed |