Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13123172 | 0.92 | CASP2 (0.60) | CASP2EPHX1MEN1KMT2ANAAA | |
| Hydrochloric Acid SCHEMBL28469891 | 0.90 | CASP2 (0.58) | CASP2EPHX1MEN1KMT2ANAAA | |
| SCHEMBL16348300 | 0.84 | CASP2 (0.46) | CASP2EPHX1MEN1KMT2ANAAA | |
| SCHEMBL8956435 | 0.84 | MEN1 (0.43) | CASP2MEN1KMT2ANAAADNM1 | |
| SCHEMBL7064816 | 0.83 | EPHX2 (0.60) | CNR1 | |
| SCHEMBL8956687 | 0.81 | MEN1 (0.45) | CASP2EPHX1MEN1KMT2ANAAA | |
| SCHEMBL4578248 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2ANAAAFAAHHPGD | |
| SCHEMBL13970681 | 0.81 | DNM1 (0.55) | CASP2EPHX1MEN1KMT2ANAAA | |
| SCHEMBL4578245 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2AFAAHHPGD | |
| SCHEMBL8747854 | 0.80 | CASP2 (0.55) | CASP2EPHX1MEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689875-B1 | USE OF TRIAZOLOPYRIMIDINE, TRIAZOLOPYRIDINE COMPOUNDS AND COMPOSITION THEREOF FOR TREATING PRC2-MEDIATED DISEASES | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2021-10-13 | — | — | EP | disclosed |