Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956687 | 0.93 | MEN1 (0.45) | MEN1KMT2AGAADNM1ALDH1A1 | |
| SCHEMBL8956368 | 0.88 | ALDH1A1 (0.40) | MEN1KMT2AGAADNM1ALDH1A1 | |
| SCHEMBL23912654 | 0.84 | CASP2 (0.48) | MEN1KMT2ADNM1CASP2HPGD | |
| SCHEMBL8956661 | 0.82 | MEN1 (0.43) | MEN1KMT2ADNM1ALDH1A1MAPK1 | |
| SCHEMBL13123172 | 0.81 | CASP2 (0.60) | MEN1KMT2ADNM1CASP2NAAA | |
| SCHEMBL24393605 | 0.79 | DNM1 (0.35) | MEN1KMT2AGAADNM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28469891 | 0.79 | CASP2 (0.58) | MEN1KMT2ADNM1CASP2NAAA | |
| SCHEMBL8957018 | 0.79 | ALDH1A1 (0.36) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL4578248 | 0.78 | ALDH1A1 (0.41) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL4578245 | 0.78 | ALDH1A1 (0.41) | MEN1KMT2AGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514282-B1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | OREAL (FR) | 1996-04-10 | — | — | EP | claimed |
| US-5583257-A | REDUCING AGENTS FOR PERMANENT HAIR; ODORLESS | L'OREAL (FR) | 1996-12-10 | — | — | US | disclosed |
| US-5449805-A | Permanent waves for hair | L'OREAL (FR) | 1995-09-12 | — | — | US | disclosed |
| US-5334377-A | Reduction of the disulfide bond of keratin; the oxidation | L'OREAL (FR) | 1994-08-02 | — | — | US | disclosed |