Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12456123 | 0.81 | UHRF1 (0.35) | CYP1A2MAPK1 | |
| SCHEMBL29781537 | 0.81 | UHRF1 (0.35) | CYP1A2MAPK1 | |
| SCHEMBL626900 | 0.80 | L3MBTL1 (0.44) | CYP1A2LIPE | |
| SCHEMBL30508802 | 0.78 | LPL (0.35) | LIPEMAPK1 | |
| SCHEMBL15342466 | 0.78 | EGFR (0.31) | MAPK1 | |
| SCHEMBL1192473 | 0.78 | LPL (0.35) | LIPEMAPK1 | |
| SCHEMBL15051210 | 0.76 | ABL1 (0.46) | — | |
| SCHEMBL29652860 | 0.75 | NNMT (0.37) | NNMTLIPE | |
| SCHEMBL20519939 | 0.75 | NNMT (0.37) | NNMTLIPE | |
| SCHEMBL30508803 | 0.75 | LPL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094325-B1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-10-13 | — | — | EP | disclosed |