Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192473 | 1.00 | LPL (0.35) | LPLLIPGCXCR2MAPK1LIPE | |
| SCHEMBL22766300 | 0.84 | LPL (0.36) | LPLLIPGCXCR2JAK2BTK | |
| SCHEMBL29781537 | 0.82 | UHRF1 (0.35) | LPLLIPGMAPK1USP30 | |
| SCHEMBL12456123 | 0.82 | UHRF1 (0.35) | LPLLIPGMAPK1USP30 | |
| SCHEMBL16043086 | 0.81 | EGFR (0.36) | LPLLIPGCXCR2LIPEJAK2 | |
| SCHEMBL15342466 | 0.79 | EGFR (0.31) | MAPK1JAK2BTKUSP30EGFR | |
| SCHEMBL23181503 | 0.79 | AAK1 (0.34) | USP30 | |
| SCHEMBL30508705 | 0.79 | AAK1 (0.34) | USP30 | |
| SCHEMBL19743736 | 0.79 | LIPE (0.35) | LIPEUSP30 | |
| SCHEMBL23912778 | 0.78 | NNMT (0.38) | MAPK1LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466258-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |