Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12696914 | 0.82 | IDO1 (0.40) | IDO1NFE2L2TUBB4ATUBBTUBA3C | |
| SCHEMBL24313608 | 0.79 | L3MBTL1 (0.41) | KDM4EMEN1KMT2AMAPTHTT | |
| SCHEMBL9018791 | 0.78 | MAPT (0.38) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23912787 | 0.78 | ACHE (0.56) | KDM4EMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL3783961 | 0.76 | MAPT (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2874102 | 0.76 | KDM4E (0.39) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31260836 | 0.74 | HTT (0.40) | MEN1KMT2AMAPTHTTFFAR1 | |
| SCHEMBL1712860 | 0.74 | CA1 (0.55) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL166380 | 0.73 | NFE2L2 (0.61) | NFE2L2KDM4EPDGFRBPDGFRACA12 | |
| SCHEMBL18472613 | 0.73 | NFE2L2 (0.61) | NFE2L2KDM4EPDGFRBPDGFRACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094325-B1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-10-13 | — | — | EP | disclosed |