SCHEMBL23912853

SCHEMBL23912853

CC1CC2CC(C)CC(NC(=O)N3CC(OC(c4ccc(Cl)cc4)c4ccc(Cl)cc4)C3)(C1)C2

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
TSHR P16473 1/20 0.47
ALOX12 P18054 1/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
EPHX2 P34913 1/20 0.44
FAAH O00519 10/20 0.43
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
CNR2 P34972 1/20 0.40
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4075603 0.92 LMNA (0.52) LMNATSHRALOX12HTTNPSR1
SCHEMBL24454992 0.90 CNR2 (0.40) LMNATSHRALOX12HTTNPSR1
SCHEMBL23912846 0.87 FAAH (0.43) FAAH
SCHEMBL4182413 0.84 LMNA (0.51) LMNATSHRALOX12HTTNPSR1
SCHEMBL4182411 0.84 LMNA (0.51) LMNATSHRALOX12HTTNPSR1
SCHEMBL4080235 0.84 FAAH (0.42) LMNATSHRALOX12HTTNPSR1
SCHEMBL24454997 0.84 CNR2 (0.44) LMNATSHRALOX12HTTNPSR1
SCHEMBL4084625 0.81 CNR2 (0.47) LMNATSHRALOX12HTTNPSR1
SCHEMBL23912854 0.81 FAAH (0.40) LMNATSHRALOX12HTTNPSR1
SCHEMBL4189090 0.80 FAAH (0.64) FAAHCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022109043-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE ANEBULO PHARMACEUTICALS, INC. (US) 2022-05-27 WO disclosed
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose ANEBULO PHARMACEUTICALS, INC. (US) 2021-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose CNR1, CNR2, FAAH LMNA 2773/4885TSHR 1458/4885ALOX12 365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.