SCHEMBL23912854

SCHEMBL23912854

CC1CC2=CCC(NC(=O)N3CC(OC(c4ccc(Cl)cc4)c4ccc(Cl)cc4)C3)(C2)C1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FAAH O00519 15/20 0.40
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36
CYP2C19 P33261 1/20 0.36
KCNH2 Q12809 1/20 0.36
MGLL Q99685 1/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24433967 0.88 FAAH (0.41) FAAHCNR1
SCHEMBL24433946 0.85 FAAH (0.34) FAAHLMNATSHRALOX12HTT
SCHEMBL23912853 0.81 LMNA (0.47) FAAHCNR2LMNATSHRALOX12
SCHEMBL4075603 0.78 LMNA (0.52) FAAHCNR1CNR2CYP2C19KCNH2
SCHEMBL4080235 0.76 FAAH (0.42) FAAHCNR1CNR2CYP2C19KCNH2
SCHEMBL24454992 0.71 CNR2 (0.40) CNR2LMNATSHRALOX12HTT
SCHEMBL4080228 0.70 CNR1 (0.48) FAAHCNR1CNR2
SCHEMBL23912846 0.70 FAAH (0.43) FAAHCNR1
SCHEMBL4182413 0.70 LMNA (0.51) FAAHCNR1CNR2LMNATSHR
SCHEMBL4182411 0.70 LMNA (0.51) FAAHCNR1CNR2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220151990-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE ANEBULO PHARMACEUTICALS, INC. 2022-05-19 US disclosed
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose ANEBULO PHARMACEUTICALS, INC. (US) 2021-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220151990-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE CNR1, CNR2, FAAH FAAH 3/4885CNR1 1/4885CNR2 2/4885
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose CNR1, CNR2, FAAH FAAH 3/4885CNR1 1/4885CNR2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.