Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OXGR1 | Q96P68 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156078 | 0.88 | RXFP1 (0.35) | NPC1THRBRXFP1ALDH1A1KDM4E | |
| SCHEMBL20156349 | 0.85 | ITGB3 (0.49) | ITGB3ITGAV | |
| SCHEMBL20156279 | 0.83 | SUCNR1 (0.37) | SUCNR1ITGB3ITGAVOXGR1 | |
| SCHEMBL20156364 | 0.80 | SUCNR1 (0.39) | SUCNR1ITGB3ITGAVOXGR1BDKRB1 | |
| SCHEMBL23912916 | 0.78 | MAPT (0.40) | SUCNR1KDM4EMEN1KMT2AOXGR1 | |
| SCHEMBL20156301 | 0.77 | ITGB3 (0.57) | ITGB3ITGAV | |
| SCHEMBL20156083 | 0.77 | ITGB3 (0.40) | ALDH1A1ITGB3ITGAVPDE2AMEN1 | |
| SCHEMBL20156077 | 0.77 | NPC1 (0.40) | NPC1THRBRXFP1SUCNR1ALDH1A1 | |
| SCHEMBL20156079 | 0.75 | SUCNR1 (0.38) | SUCNR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL20156362 | 0.73 | CYP1A2 (0.39) | SUCNR1MEN1KMT2AOXGR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |