SCHEMBL23913790

SCHEMBL23913790

C=C1C(=O)O[C@H](c2ccc(C)cc2)[C@@H]1c1ccc(C#N)cc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
CYP2A6 P11509 1/20 0.46
KDM1A O60341 7/20 0.43
TNKS O95271 1/20 0.36
FADS1 O60427 4/20 0.34
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
KCNH2 Q12809 1/20 0.33
CYP19A1 P11511 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23914279 1.00 ALDH1A1 (0.46) ALDH1A1CYP2A6KDM1ATNKSFADS1
SCHEMBL23913791 0.88 TNKS (0.40) ALDH1A1KDM1ATNKSFADS1CYP19A1
SCHEMBL23914431 0.88 TNKS (0.40) ALDH1A1KDM1ATNKSFADS1CYP19A1
SCHEMBL23914349 0.88 ALDH1A1 (0.39) ALDH1A1TNKSCYP19A1SLC6A3
SCHEMBL23914317 0.86 MAOB (0.39) TNKSFADS1CYP19A1
SCHEMBL23913941 0.86 CA2 (0.46) TNKSCYP19A1
SCHEMBL23913787 0.85 KDM1A (0.46) ALDH1A1KDM1A
SCHEMBL23914087 0.83 MAOB (0.41) ALDH1A1TNKSCYP19A1
SCHEMBL23914439 0.83 MAOB (0.41) ALDH1A1TNKSCYP19A1
SCHEMBL23913793 0.78 ACHE (0.44) ALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS PURDUE RESEARCH FOUNDATION (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS MIF, LTA, MGAM ALDH1A1 2164/4885CYP2A6 969/4885KDM1A 3481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.