SCHEMBL23913938

SCHEMBL23913938

C=C1C(=O)O[C@H](c2ccc(OC)cc2)[C@@H]1c1cccc(Br)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
KMT2A Q03164 3/20 0.40
CYP3A4 P08684 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
MAPT P10636 5/20 0.37
MAOB P27338 3/20 0.37
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
CYP19A1 P11511 1/20 0.37
THRB P10828 2/20 0.37
POLB P06746 1/20 0.37
HTT P42858 1/20 0.37
BLM P54132 1/20 0.37
NPBWR1 P48145 1/20 0.37
GABRP O00591 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23914267 0.87 KMT2A (0.44) ALDH1A1KMT2ACYP3A4SMN1; SMN2MEN1
SCHEMBL23914083 0.85 ALDH1A1 (0.45) ALDH1A1KMT2ACYP3A4SMN1; SMN2MEN1
SCHEMBL23913947 0.84 ALDH1A1 (0.52) ALDH1A1CYP3A4SMN1; SMN2MAPTMAOB
SCHEMBL23914088 0.84 ALDH1A1 (0.52) ALDH1A1CYP3A4SMN1; SMN2MAPTMAOB
SCHEMBL23913964 0.81 CYP2C19 (0.36) ALDH1A1KMT2ACYP3A4MEN1CYP2D6
SCHEMBL23913793 0.80 ACHE (0.44) ALDH1A1KMT2ASMN1; SMN2MEN1MAPT
SCHEMBL23914374 0.78 EDNRA (0.42) ALDH1A1KMT2ACYP3A4SMN1; SMN2MEN1
SCHEMBL23914366 0.76 CYP2C19 (0.41) ALDH1A1SMN1; SMN2CYP2C19MAPTMAOB
SCHEMBL23913787 0.75 KDM1A (0.46) ALDH1A1KMT2ACYP3A4SMN1; SMN2MEN1
SCHEMBL14427629 0.74 CRHBP (0.47) ALDH1A1KMT2AMEN1MAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS PURDUE RESEARCH FOUNDATION (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS MIF, LTA, MGAM ALDH1A1 2164/4885KMT2A 2354/4885CYP3A4 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.