Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.31 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MYB | P10242 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23914317 | 0.82 | MAOB (0.39) | TNKSCYP19A1NPC1 | |
| SCHEMBL23913791 | 0.82 | TNKS (0.40) | TNKSCYP19A1KDM4EALDH1A1NPC1 | |
| SCHEMBL23914431 | 0.82 | TNKS (0.40) | TNKSCYP19A1KDM4EALDH1A1NPC1 | |
| SCHEMBL23913942 | 0.81 | ALDH1A1 (0.38) | CYP19A1KDM4EALDH1A1TSHR | |
| SCHEMBL23914310 | 0.78 | MAPK1 (0.37) | TNKSCYP19A1ALDH1A1 | |
| SCHEMBL23913790 | 0.77 | ALDH1A1 (0.46) | TNKSCYP19A1ALDH1A1 | |
| SCHEMBL23913941 | 0.77 | CA2 (0.46) | TNKSCYP19A1 | |
| SCHEMBL23914279 | 0.77 | ALDH1A1 (0.46) | TNKSCYP19A1ALDH1A1 | |
| SCHEMBL23913787 | 0.74 | KDM1A (0.46) | ALDH1A1CASP1CASP7NPC1RAB9A | |
| SCHEMBL23914347 | 0.73 | HDAC4 (0.38) | ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317099-A1 | SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317099-A1 | SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS | MIF, LTA, MGAM | TNKS 556/4885CYP19A1 2911/4885KDM4E 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.