SCHEMBL23914284

SCHEMBL23914284

O=C1OC2(CCCC2)CC1CN1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 2/20 0.37
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
MITF O75030 1/20 0.34
POLB P06746 1/20 0.34
CHRNA7 P36544 10/20 0.33
CHRM5 P08912 1/20 0.32
ADRA2C P18825 1/20 0.32
SSTR5 P35346 1/20 0.32
KCNH2 Q12809 1/20 0.32
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16575248 0.87 HSD11B1 (0.36) KMT2AMEN1MITFPOLB
SCHEMBL23913951 0.79 L3MBTL1 (0.41) METAP1KMT2AMEN1MITFPOLB
SCHEMBL16575250 0.73 METAP1 (0.34) METAP1CHRNA7KCNH2
SCHEMBL16575251 0.73 MEN1 (0.35) METAP1KMT2AMEN1MITFPOLB
SCHEMBL16575259 0.71 POLB (0.34) METAP1KMT2AMEN1MITFPOLB
SCHEMBL16575256 0.70 CHRNA7 (0.33) METAP1KMT2AMEN1MITFPOLB
SCHEMBL23914336 0.70 METAP1 (0.43) METAP1CHRNA7KCNH2LMNA
SCHEMBL7287901 0.67 KDM4E (0.33)
SCHEMBL7294281 0.67 KDM4E (0.33)
SCHEMBL12440638 0.66 KDM4E (0.36) KMT2APOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS PURDUE RESEARCH FOUNDATION (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS MIF, LTA, MGAM METAP1 890/4885KMT2A 2354/4885MEN1 1587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.