Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287901 | 1.00 | KDM4E (0.33) | KDM4EHTTATMICAM1 | |
| SCHEMBL12440638 | 0.81 | KDM4E (0.36) | KDM4EHTTATM | |
| SCHEMBL10597112 | 0.77 | KDM4E (0.33) | KDM4EHTTATM | |
| SCHEMBL4611119 | 0.77 | KDM4E (0.33) | KDM4EHTTATM | |
| SCHEMBL5352573 | 0.77 | KDM4E (0.33) | KDM4EHTTATM | |
| SCHEMBL4612169 | 0.74 | LMNA (0.32) | KDM4EHTTATM | |
| SCHEMBL5665984 | 0.69 | — | — | |
| SCHEMBL5569224 | 0.68 | — | — | |
| SCHEMBL23914284 | 0.67 | METAP1 (0.37) | — | |
| SCHEMBL17954008 | 0.67 | OPRK1 (0.36) | KDM4EHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876359-A | HYPOTENSIVE, ANGIOTENSIN ENZYME INHIBITOR | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| EP-0266568-A2 | Novel gamma-butyrolactone derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |