Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15132941 | 0.83 | LMNA (0.59) | MAPK1THRBTSHRSMN1; SMN2LMNA | |
| SCHEMBL13160074 | 0.83 | KDM4E (0.48) | MAPK1TSHRSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL20381754 | 0.82 | MAPK1 (0.71) | MAPK1THRBTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6531818 | 0.82 | MAPK1 (0.75) | MAPK1THRBTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4198448 | 0.81 | MAPK1 (0.56) | MAPK1THRBTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL30334879 | 0.79 | MAPK1 (0.67) | MAPK1THRBTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL1979734 | 0.79 | KDM4E (0.67) | MAPK1TSHRSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL1011398 | 0.79 | THRB (0.72) | MAPK1THRBTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10500983 | 0.79 | MAPK1 (0.67) | MAPK1THRBTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL5651111 | 0.79 | MAPK1 (0.67) | MAPK1THRBTSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317160-A1 | 3,4-THIAZOLO-STEROIDS AND METHODS OF MAKING AND USING THE SAME | Arkansas State University - Jonesboro | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317160-A1 | 3,4-THIAZOLO-STEROIDS AND METHODS OF MAKING AND USING THE SAME | HSD17B7, HSD17B3, NR3C2 | MAPK1 3636/4885THRB 404/4885TSHR 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.