Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CD4 | P01730 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22077195 | 0.85 | PDGFRB (0.40) | NPC1RAB9AMEN1KMT2APDGFRB | |
| SCHEMBL1683406 | 0.85 | HTR6 (0.46) | RAB9AMEN1KMT2AHTR6KDM4E | |
| SCHEMBL22074019 | 0.81 | ALDH1A1 (0.41) | NPC1RAB9AMEN1KMT2APDGFRB | |
| SCHEMBL2433007 | 0.81 | MEN1 (0.64) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL22077191 | 0.80 | CYP2C19 (0.53) | MEN1KMT2APDGFRBPDGFRACD4 | |
| SCHEMBL4234276 | 0.78 | MEN1 (0.54) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL7515939 | 0.77 | ENPP3 (0.50) | HTR6KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL1773113 | 0.77 | CXCL8 (0.43) | MEN1KMT2AHTR6KDM4EALDH1A1 | |
| SCHEMBL1683455 | 0.75 | KDM4E (0.44) | MEN1KMT2ACD4HTR6KDM4E | |
| SCHEMBL22494274 | 0.73 | HTR6 (0.44) | RAB9AMEN1KMT2AHTR6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892616-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |