Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23915977 | 0.88 | KCNH2 (0.35) | MAP4K4PIK3CAKCNH2MINK1PI4KB | |
| SCHEMBL21135415 | 0.88 | KCNH2 (0.41) | MAP4K4PIK3CAKCNH2MINK1PI4KB | |
| SCHEMBL23916420 | 0.79 | HPGDS (0.36) | PIK3CAPI4KBPDE10A | |
| SCHEMBL20329856 | 0.79 | PIK3CA (0.40) | PIK3CAKCNH2PI4KB | |
| SCHEMBL23916453 | 0.78 | GLA (0.34) | — | |
| SCHEMBL23916020 | 0.77 | PDE5A (0.37) | PIK3CAPI4KB | |
| SCHEMBL23915989 | 0.76 | PDE3B (0.31) | MAP4K4 | |
| SCHEMBL23910009 | 0.76 | MAP3K11 (0.41) | PIK3CA | |
| SCHEMBL21072312 | 0.76 | MAPT (0.33) | — | |
| SCHEMBL20329236 | 0.76 | KCNH2 (0.41) | PIK3CAKCNH2PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | MAP4K4 2906/4885PIK3CA 3273/4885KCNH2 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.