Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23916420 | 0.86 | HPGDS (0.36) | PDE3BPDE3A | |
| SCHEMBL21072312 | 0.83 | MAPT (0.33) | — | |
| SCHEMBL23916453 | 0.83 | GLA (0.34) | ALOX5APFEN1 | |
| SCHEMBL14217428 | 0.82 | ALDH1A1 (0.34) | — | |
| SCHEMBL23916028 | 0.81 | CCNC (0.38) | PDE3BPDE3AMAP4K4 | |
| SCHEMBL20329236 | 0.81 | KCNH2 (0.41) | PDE3BPDE3A | |
| SCHEMBL23910009 | 0.81 | MAP3K11 (0.41) | — | |
| SCHEMBL23916377 | 0.80 | BRAF (0.39) | MAP4K4 | |
| SCHEMBL23915977 | 0.79 | KCNH2 (0.35) | MAP4K4 | |
| SCHEMBL23916498 | 0.79 | PI4KB (0.40) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | PDE3B 949/4885PDE3A 1143/4885MAP4K4 2906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.