SCHEMBL2391709

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2391431	0.89	SLC6A4 (0.45)	KMT2APTGS2PTGS1ALDH1A1BCL2L1
	SCHEMBL2389486	0.86	MAOB (0.46)	PTGS2PPARAPPARG
	SCHEMBL2393686	0.85	BCAT2 (0.48)	KMT2AFGFR1FGFR2FGFR4FGFR3
	SCHEMBL2389641	0.84	HSP90AA1 (0.47)	KMT2APTGS2PTPRCHSP90AA1HSP90AB1
	SCHEMBL2391552	0.81	NPSR1 (0.47)	KMT2APTPRCPTPN1MEN1HPGD
	SCHEMBL9890795	0.80	FGFR1 (0.46)	KMT2AFGFR1FGFR2FGFR4FGFR3
	SCHEMBL4120437	0.79	KMT2A (0.50)	KMT2AFGFR1FGFR2FGFR4FGFR3
	SCHEMBL29385679	0.79	KMT2A (0.50)	KMT2AFGFR1FGFR2FGFR4FGFR3
	SCHEMBL4886483	0.78	LMNA (0.50)	KMT2AFGFR1FGFR2FGFR4FGFR3
	SCHEMBL4873147	0.76	TRPA1 (0.46)	KMT2ABCAT2PTGS2PTPRCPTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.