Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 9/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 5/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.36 |
| ▸ | ABL1 | P00519 | 4/20 | 0.36 |
| ▸ | HCK | P08631 | 4/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.36 |
| ▸ | MTOR | P42345 | 4/20 | 0.36 |
| ▸ | PRKDC | P78527 | 4/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20793723 | 0.85 | FAAH (0.40) | BTKFGFR1FGFR3LRRK2SRC | |
| SCHEMBL23917286 | 0.80 | FGFR1 (0.41) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL9010 | 0.78 | PIK3CG (0.54) | BTKFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL13829837 | 0.76 | FLT3 (0.44) | FGFR1FGFR3SRCKDRABL1 | |
| SCHEMBL11928101 | 0.76 | PIK3CD (0.56) | BTKSRCKDREGFRPIK3CD | |
| SCHEMBL11306 | 0.75 | SRC (0.47) | SRCKDREGFRPIK3CDABL1 | |
| SCHEMBL23917564 | 0.75 | FGFR1 (0.43) | BTKFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL16665789 | 0.75 | JAK3 (0.43) | BTKFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL16665788 | 0.75 | SRC (0.42) | BTKFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20093476 | 0.74 | VRK1 (0.41) | BTKSRCKDREGFRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | BTK 1/4885FGFR1 2569/4885FGFR2 1759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.