Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 5/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23393940 | 0.85 | SIRT5 (0.39) | FURINC3AR1LMNAPOLBKMT2A | |
| SCHEMBL21103418 | 0.84 | SIRT5 (0.36) | FURINC3AR1LMNAPOLBKMT2A | |
| SCHEMBL22001947 | 0.84 | C3AR1 (0.34) | FURINC3AR1LMNAPOLBKMT2A | |
| SCHEMBL21915057 | 0.84 | C3AR1 (0.34) | FURINC3AR1LMNAPOLBKMT2A | |
| SCHEMBL1711524 | 0.84 | C3AR1 (0.44) | FURINC3AR1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20159819 | 0.84 | FURIN (0.36) | FURINC3AR1LMNAPOLBKMT2A | |
| SCHEMBL24490420 | 0.84 | C3AR1 (0.34) | FURINC3AR1LMNAPOLBKMT2A | |
| SCHEMBL23736705 | 0.84 | FURIN (0.36) | FURINC3AR1LMNAPOLBKMT2A | |
| SCHEMBL20795891 | 0.84 | FURIN (0.36) | FURINC3AR1LMNAPOLBKMT2A | |
| SCHEMBL16091799 | 0.84 | SIRT5 (0.36) | FURINC3AR1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892305-A1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | Sutro Biopharma, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |