Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | MGAM | O43451 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 6/20 | 0.64 |
| ▸ | SI | P14410 | 6/20 | 0.64 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.61 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.61 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3691525 | 0.98 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL6538646 | 0.96 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL28206720 | 0.90 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| Sulfuric Acid SCHEMBL2380188 | 0.89 | CSNK2A2 (0.60) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| Sulfuric Acid SCHEMBL396801 | 0.89 | CSNK2A2 (0.60) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| Phosphoric Acid SCHEMBL16033968 | 0.89 | CSNK2A2 (0.60) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL11431183 | 0.83 | MGAM (0.68) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL9018567 | 0.83 | ALDH1A1 (0.61) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL28851907 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL2213286 | 0.80 | ALDH1A1 (0.59) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354962-B | 12-Nitrogen substituted matric acid ester derivative, preparation method and application thereof | 广西大学 | 2025-01-07 | — | — | CN | claimed |
| CN-118255729-A | Method for synthesizing 2-amino-5-substituted-1, 3, 4-thiadiazole | 陕西科技大学 | 2024-06-28 | — | — | CN | claimed |
| CN-116354962-A | 12-nitrogen substituted matric acid ester derivative, preparation method and application thereof | 广西大学 | 2023-06-30 | — | — | CN | claimed |
| CN-109400724-B | Thiadiazole urea-containing acetylated starch and preparation method and application thereof | 中国科学院烟台海岸带研究所 | 2021-04-02 | — | — | CN | claimed |
| CN-107488174-B | Phenyl-substituted thiadiazole thiazolinone compound and preparation method and application thereof | 南宁师范大学 | 2020-09-22 | — | — | CN | claimed |
| EP-2526098-B1 | NITROGEN-CONTAINING HETEROARYL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2018-07-11 | — | — | EP | claimed |
| CN-107501342-A | The preparation method of the ferrocenyl imidazo of 2 phenyl 6 [2,1 b] 1,3,4 thiadiazoles | 张家港贸安贸易有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-107488174-A | Phenyl substitution thiadiazole thiazolinone compound and its preparation method and application | 广西师范学院 | 2017-12-19 | — | — | CN | claimed |
| EP-3181568-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | Siga Technologies, Inc. (US) | 2017-06-21 | — | — | EP | claimed |
| EP-2400845-B1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | SIGA TECH INC (US) | 2017-02-22 | — | — | EP | claimed |
| US-20140275546-A1 | AZAADAMANTANE FORMATE ESTER AND PROCESS FOR PREPARING AZAADAMANTANE DERIVATIVES | ABBVIE INC. (US) | 2014-09-18 | — | — | US | claimed |
| US-8470820-B2 | Nitrogen-containing heteroaryl derivatives | HOFFMAN-LA ROCHE INC. (US) | 2013-06-25 | — | — | US | claimed |
| EP-2400845-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | Siga Technologies, Inc. (US) | 2012-01-04 | — | — | EP | claimed |
| WO-2010099166-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | SIGA TECHNOLOGIES, INC. (US) | 2010-09-02 | — | — | WO | claimed |
| EP-1658072-A4 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PROD INC (US) | 2009-03-25 | — | — | EP | claimed |
| US-20070270426-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER INC. | 2007-11-22 | — | — | US | claimed |
| US-7253195-B2 | Compounds for the treatment of neurodegenerative disorders | PFIZER INC (US) | 2007-08-07 | — | — | US | claimed |
| EP-1658072-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Pfizer Products Inc. (US) | 2006-05-24 | — | — | EP | claimed |
| WO-2005020991-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PRODUCTS, INC. (US) | 2005-03-10 | — | — | WO | claimed |
| US-20050043372-A1 | Compounds for the treatment of neurodegenerative disorders | PFIZER, INC. (US) | 2005-02-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270426-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | APP, BACE1, PSEN1 | KDM4E 3582/4885ALDH1A1 2945/4885HSD17B10 3429/4885 |
| US-20140275546-A1 | AZAADAMANTANE FORMATE ESTER AND PROCESS FOR PREPARING AZAADAMANTANE DERIVATIVES | DHRS9, GRHPR, DECR1 | KDM4E 76/4885ALDH1A1 449/4885HSD17B10 134/4885 |
| US-20050043372-A1 | Compounds for the treatment of neurodegenerative disorders | APP, BACE1, PSEN1 | KDM4E 3582/4885ALDH1A1 2945/4885HSD17B10 3429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.