Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | XDH | P47989 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.65 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.65 |
| ▸ | TP53 | P04637 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | IPMK | Q8NFU5 | 5/20 | 0.65 |
| ▸ | IP6K2 | Q9UHH9 | 5/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.65 |
| ▸ | BCHE | P06276 | 4/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14769773 | 0.93 | MEN1 (0.76) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL8042944 | 0.90 | ABCB1 (0.81) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL9909444 | 0.89 | MEN1 (0.75) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL12455833 | 0.88 | TP53 (0.57) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL12455834 | 0.88 | CYP1A1 (0.79) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL14254533 | 0.87 | MEN1 (0.58) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL12305080 | 0.87 | MEN1 (0.73) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL28430943 | 0.82 | TP53 (0.60) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL9565912 | 0.81 | POLH (0.65) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL16682485 | 0.79 | FBP1 (0.78) | MEN1KMT2ACYP1A2ABCB1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317497-A1 | MONBRETIN A (MBA) SYNTHESIS USING A HETEROLOGOUS NUCLEIC ACID(S) ENCODING A MBA PATHWAY ENZYME | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2021-10-14 | — | — | US | disclosed |