SCHEMBL23923374

SCHEMBL23923374

CCCCCCCCCCCCOC(=O)CCC(CP(=O)(OCC)OCC)C(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.39
PLA2G2A P14555 2/20 0.39
NAAA Q02083 1/20 0.39
DGKA P23743 1/20 0.39
P2RY10 O00398 4/20 0.38
GPR34 Q9UPC5 2/20 0.38
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
LPAR6 P43657 1/20 0.36
LPAR1 Q92633 1/20 0.36
LPAR4 Q99677 1/20 0.36
LPAR5 Q9H1C0 1/20 0.36
LPAR2 Q9HBW0 1/20 0.36
LPAR3 Q9UBY5 1/20 0.36
ENPP2 Q13822 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21805185 0.93 DGKA (0.46) PLA2G2ADGKAP2RY10GPR34LPAR6
SCHEMBL21804584 0.82 DGKA (0.49) PLA2G2ADGKAP2RY10GPR34LPAR6
SCHEMBL21805170 0.82 CASP2 (0.43) NAAALPAR1LPAR2LPAR3ENPP2
SCHEMBL19220632 0.80 SMN1; SMN2 (0.39)
SCHEMBL17533548 0.79 DGKA (0.34) DGKAP2RY10GPR34LPAR6LPAR1
SCHEMBL21804792 0.79 PPARD (0.40)
SCHEMBL7536183 0.74 NAAA (0.44) HTR2CNAAADGKAP2RY10GPR34
SCHEMBL2350141 0.74 NAAA (0.53) HTR2CNAAADGKAP2RY10GPR34
SCHEMBL2350510 0.74 NAAA (0.53) HTR2CNAAADGKAP2RY10GPR34
SCHEMBL2353999 0.74 NAAA (0.53) HTR2CNAAADGKAP2RY10GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166087-B Screening agent and use thereof 恩多塞特公司 2024-05-10 CN disclosed
US-20210323985-A1 SHIELDING AGENTS AND THEIR USE ENDOCYTE INC (US) 2021-10-21 US disclosed
CN-113166087-A Shielding agent and application thereof 恩多塞特公司 2021-07-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210323985-A1 SHIELDING AGENTS AND THEIR USE PSMA6, PSMA2, PSMA1 HTR2C 4438/4885PLA2G2A 920/4885NAAA 2166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.