SCHEMBL23924190

SCHEMBL23924190

NCCCCCc1ccc([SiH3])c(CCCCCN)c1CCCCCN

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 5/20 0.37
MAOA P21397 1/20 0.36
MPO P05164 4/20 0.34
SLC6A4 P31645 1/20 0.33
TLR8 Q9NR97 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23923950 0.92 MPO (0.32) MAOAMPOSLC6A4
SCHEMBL21130811 0.78 DNM1 (0.52) TLR8
SCHEMBL3412063 0.78 DNM1 (0.52) TLR8
SCHEMBL28814041 0.77 TYR (0.43) HRH1MAOA
SCHEMBL3886767 0.76 TYR (0.41) TLR8
SCHEMBL4190211 0.76
SCHEMBL8589255 0.73 MAOA (0.48) HRH1MAOAMPOSLC6A4TLR8
SCHEMBL28396089 0.69 TAAR1 (0.41) MAOAMPOSLC6A4TLR8
SCHEMBL17508106 0.68 MAOA (0.43) HRH1MAOAMPOSLC6A4TLR8
SCHEMBL27980900 0.68 TAAR1 (0.47) HRH1MAOAMPOSLC6A4TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3841167-B1 COMPOSITION FOR SILICONE RUBBER MASSES NITROCHEMIE GMBH (DE) 2023-02-22 EP disclosed
US-20210324195-A1 Composition for Silicone Rubber Masses NITROCHEMIE ASCHAU GMBH (DE) 2021-10-21 US disclosed