Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319587 | 0.91 | MAPT (0.53) | IDO1TAAR1MAPTBCHEACHE | |
| SCHEMBL25464628 | 0.89 | BCHE (0.61) | IDO1TAAR1MAPTBCHEACHE | |
| SCHEMBL25930307 | 0.87 | IDO1 (0.52) | IDO1TAAR1MAPTBCHEACHE | |
| SCHEMBL23927279 | 0.85 | IDO1 (0.59) | IDO1TAAR1MAPTBCHEACHE | |
| SCHEMBL7531508 | 0.83 | IDO1 (0.49) | IDO1TAAR1MAPTBCHEACHE | |
| SCHEMBL23796962 | 0.82 | PYCR1 (0.47) | IDO1TAAR1MAPTBCHEACHE | |
| SCHEMBL5534307 | 0.81 | IDO1 (0.55) | IDO1TAAR1MAPTBCHEACHE | |
| SCHEMBL5534304 | 0.81 | IDO1 (0.55) | IDO1TAAR1MAPTBCHEACHE | |
| SCHEMBL24188338 | 0.81 | IDO1 (0.55) | IDO1TAAR1MAPTBCHEACHE | |
| SCHEMBL5167680 | 0.80 | TAAR1 (0.53) | IDO1TAAR1MAPTBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139281-B1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | UNIV HEIDELBERG (DE) | 2024-05-08 | — | — | EP | disclosed |
| US-20230151054-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230151054-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2023-05-18 | — | — | US | disclosed |
| EP-4139281-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2023-03-01 | — | — | EP | disclosed |
| CN-112321469-B | Synthetic method of dibenzyl sulfide | 成都理工大学 | 2022-07-12 | — | — | CN | disclosed |
| WO-2021214243-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021214243-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2021-10-28 | — | — | WO | disclosed |
| EP-3901135-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2021-10-27 | — | — | EP | disclosed |
| CN-112321469-A | Synthetic method of dibenzyl sulfide | 成都理工大学 | 2021-02-05 | — | — | CN | disclosed |
| CN-106117096-B | A kind of synthetic method of asymmetric thioether | 苏州大学 | 2018-01-19 | — | — | CN | disclosed |
| CN-106117096-A | A kind of synthetic method of asymmetric thioether | 苏州大学 | 2016-11-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151054-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | TST, CBS, CTH | IDO1 1812/4885TAAR1 3595/4885MAPT 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.