SCHEMBL2392739

SCHEMBL2392739

O=C(O)c1ccc2nc3c(nc2c1)-c1cccc2cccc-3c12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.67
MEN1 O00255 5/20 0.67
KMT2A Q03164 5/20 0.67
RXFP1 Q9HBX9 2/20 0.67
PKM P14618 1/20 0.67
HTT P42858 1/20 0.67
ALDH1A1 P00352 6/20 0.62
KDM4E B2RXH2 6/20 0.62
HPGD P15428 4/20 0.62
NPC1 O15118 4/20 0.62
GAA P10253 3/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
MAPT P10636 5/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
POLB P06746 2/20 0.55
CYP1A2 P05177 1/20 0.55
NSD2 O96028 1/20 0.55
THRB P10828 1/20 0.55
PABPC1 P11940 1/20 0.55
TNNI3 P19429 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3215265 0.98 RAB9A (0.65) RAB9AMEN1KMT2ARXFP1PKM
SCHEMBL13658060 0.86 CYP1A2 (0.54) RAB9AMEN1KMT2ARXFP1PKM
SCHEMBL2396254 0.85 MEN1 (0.56) RAB9AMEN1KMT2ARXFP1PKM
SCHEMBL2395393 0.85 MEN1 (0.56) RAB9AMEN1KMT2ARXFP1PKM
Ammonia Solution, Strong SCHEMBL2395604 0.84 MEN1 (0.55) RAB9AMEN1KMT2ARXFP1PKM
SCHEMBL824436 0.84 RAB9A (0.55) RAB9AMEN1KMT2ARXFP1PKM
Ammonia Solution, Strong SCHEMBL2396268 0.84 MEN1 (0.55) RAB9AMEN1KMT2ARXFP1PKM
SCHEMBL824444 0.84 RAB9A (0.55) RAB9AMEN1KMT2ARXFP1PKM
Ammonia Solution, Strong SCHEMBL2395606 0.84 MEN1 (0.55) RAB9AMEN1KMT2ARXFP1PKM
Ammonia Solution, Strong SCHEMBL2396272 0.84 MEN1 (0.55) RAB9AMEN1KMT2ARXFP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8253899-B2 Birefringent film NITTO DENKO CORPORATION (JP) 2012-08-28 US disclosed
US-8253899-B2 Birefringent film NITTO DENKO CORPORATION (JP) 2012-08-28 US disclosed
US-8253899-B2 Birefringent film NITTO DENKO CORPORATION (JP) 2012-08-28 US disclosed
US-8023098-B2 Production method for birefringent film, birefringent film, and laminate NITTO DENKO CORPORATION (JP) 2011-09-20 US disclosed
US-8023098-B2 Production method for birefringent film, birefringent film, and laminate NITTO DENKO CORPORATION (JP) 2011-09-20 US disclosed
US-8023098-B2 Production method for birefringent film, birefringent film, and laminate NITTO DENKO CORPORATION (JP) 2011-09-20 US disclosed
US-8021572-B2 Optical laminate, polarizing plate, image display, and process for producing an optical laminate NITTO DENKO CORPORATION (JP) 2011-09-20 US disclosed
US-8021572-B2 Optical laminate, polarizing plate, image display, and process for producing an optical laminate NITTO DENKO CORPORATION (JP) 2011-09-20 US disclosed
US-8021572-B2 Optical laminate, polarizing plate, image display, and process for producing an optical laminate NITTO DENKO CORPORATION (JP) 2011-09-20 US disclosed
US-20100067112-A1 OPTICAL LAMINATE, POLARIZING PLATE, IMAGE DISPLAY, AND PROCESS FOR PRODUCING AN OPTICAL LAMINATE NITTO DENKO CORPORATION (JP) 2010-03-18 US disclosed
US-20100047485-A1 POLARIZING FILM NITTO DENKO CORPORATION (JP) 2010-02-25 US disclosed
US-20100047485-A1 POLARIZING FILM NITTO DENKO CORPORATION (JP) 2010-02-25 US disclosed
US-20090262297-A1 PRODUCTION METHOD FOR BIREFRINGENT FILM, BIREFRINGENT FILM, AND LAMINATE NITTO DENKO CORPORATION (JP) 2009-10-22 US disclosed
US-20090262297-A1 PRODUCTION METHOD FOR BIREFRINGENT FILM, BIREFRINGENT FILM, AND LAMINATE NITTO DENKO CORPORATION (JP) 2009-10-22 US disclosed
US-20090197065-A1 BIREFRINGENT FILM, PRODUCTION METHOD THEREOF AND USE THEREOF NITTO DENKO CORPORATION (JP) 2009-08-06 US disclosed
US-20090197065-A1 BIREFRINGENT FILM, PRODUCTION METHOD THEREOF AND USE THEREOF NITTO DENKO CORPORATION (JP) 2009-08-06 US disclosed
US-20090197065-A1 BIREFRINGENT FILM, PRODUCTION METHOD THEREOF AND USE THEREOF NITTO DENKO CORPORATION (JP) 2009-08-06 US disclosed
US-20090059370-A1 BIREFRINGENT FILM AND METHOD OF PRODUCING THE SAME NITTO DENKO CORPORATION (JP) 2009-03-05 US disclosed
US-20090059370-A1 BIREFRINGENT FILM AND METHOD OF PRODUCING THE SAME NITTO DENKO CORPORATION (JP) 2009-03-05 US disclosed
US-20070248771-A1 Acenaphtho[1,2-b]quinoxaline sulfo-and carboxy-derivative, lyotropic liquid crystal system, optically anisotropic film and method thereof and laminated optical film NITTO DENKO CORPORATION 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090197065-A1 BIREFRINGENT FILM, PRODUCTION METHOD THEREOF AND USE THEREOF C5, NQO2, C1QBP RAB9A 516/4885MEN1 191/4885KMT2A 1157/4885
US-20070248771-A1 Acenaphtho[1,2-b]quinoxaline sulfo-and carboxy-derivative, lyotropic liquid crystal system, optically anisotropic film and method thereof and laminated optical film XDH, ACE2, PNPO RAB9A 916/4885MEN1 2688/4885KMT2A 2136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.