Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501260 | 0.83 | CA2 (0.50) | FFAR1KDM4ELMNAALDH1A1 | |
| SCHEMBL3272099 | 0.80 | RXRA (0.53) | ALDH1A1 | |
| SCHEMBL9889090 | 0.79 | PTGER1 (0.57) | FFAR1FFAR4 | |
| SCHEMBL31146913 | 0.78 | ALDH1A1 (0.51) | FFAR1ALDH1A1 | |
| SCHEMBL9889127 | 0.77 | TAAR1 (0.45) | KDM4ELMNAALDH1A1 | |
| SCHEMBL27857506 | 0.76 | MEN1 (0.40) | — | |
| SCHEMBL18824993 | 0.75 | PARP1 (0.41) | — | |
| SCHEMBL29280882 | 0.75 | FFAR1 (0.65) | FFAR1FFAR4KEAP1LMNAL3MBTL1 | |
| SCHEMBL1315107 | 0.75 | TSHR (0.46) | LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL23501460 | 0.74 | ALDH1A1 (0.53) | KDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901156-A1 | NITROOXYDERIVATIVE OF ROCK KINASE INHIBITOR | Vivavision (Shanghai) Ltd (CN) | 2021-10-27 | — | — | EP | disclosed |