Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9889116 | 0.87 | PTGER1 (0.44) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL9889119 | 0.85 | LTA4H (0.48) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL9889146 | 0.79 | CCR5 (0.41) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL23927618 | 0.79 | FFAR1 (0.51) | FFAR4FFAR1 | |
| SCHEMBL11312296 | 0.76 | PTGER4 (0.65) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL16294058 | 0.75 | PTGER1 (0.64) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL2535431 | 0.75 | PTGER4 (0.64) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL2038509 | 0.74 | PTGER1 (0.67) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL27607596 | 0.73 | FFAR4 (0.59) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL1315107 | 0.72 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150369816-A1 | Polypeptide Immobilization | UNIV CHICAGO (US) | 2015-12-24 | — | — | US | disclosed |
| US-9074300-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2015-07-07 | — | — | US | disclosed |
| US-20120142547-A1 | POLYPEPTIDE IMMOBILIZATION | THE UNIVERSITY OF CHICAGO | 2012-06-07 | — | — | US | disclosed |
| US-7888055-B2 | Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity | THE UNIVERSITY OF CHICAGO (US) | 2011-02-15 | — | — | US | disclosed |
| US-20080064606-A1 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064606-A1 | Polypeptide immobilization | QPCTL, SURF4, QPCT | PTGER1 4619/4885PTGER4 4340/4885PTGER3 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.