Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HCN1 | O60741 | 2/20 | 0.33 |
| ▸ | HCN4 | Q9Y3Q4 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639458 | 0.94 | PTGDR (0.39) | PTGDRPTGDR2KMT2ALMNAGAA | |
| SCHEMBL17847413 | 0.80 | PTGDR (0.44) | PTGDRPTGDR2KMT2ALMNAALDH1A1 | |
| SCHEMBL22871193 | 0.79 | ALDH1A1 (0.47) | KMT2ALMNAGAAALDH1A1NPSR1 | |
| SCHEMBL17847398 | 0.78 | PTGDR2 (0.43) | PTGDRPTGDR2SLC6A4CETP | |
| SCHEMBL19639459 | 0.77 | PTGDR (0.44) | PTGDRPTGDR2 | |
| SCHEMBL8681745 | 0.77 | PTGDR (0.43) | PTGDRPTGDR2KMT2ALMNAALDH1A1 | |
| SCHEMBL11919524 | 0.75 | SIGMAR1 (0.49) | KMT2ALMNAALDH1A1NPSR1HPGD | |
| SCHEMBL17847410 | 0.74 | LMNA (0.31) | PTGDRPTGDR2KMT2ALMNAGAA | |
| SCHEMBL8751778 | 0.74 | L3MBTL1 (0.47) | LMNAGAAALDH1A1NPSR1SLC6A2 | |
| SCHEMBL28642852 | 0.74 | PTGDR (0.35) | PTGDRPTGDR2GAASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233806-B1 | HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RES & DEV (FR) | 2021-10-27 | — | — | EP | disclosed |