SCHEMBL23928730

SCHEMBL23928730

N=C(N)NCCCCOP(N)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
LPAR3 Q9UBY5 4/20 0.32
LPAR2 Q9HBW0 3/20 0.32
LPAR1 Q92633 2/20 0.32
S1PR2 O95136 2/20 0.32
S1PR1 P21453 2/20 0.32
S1PR3 Q99500 2/20 0.32
S1PR5 Q9H228 1/20 0.32
SAT1 P21673 1/20 0.31
SPHK1 Q9NYA1 3/20 0.31
ALB P02768 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29904263 0.95 ALOX15 (0.39) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL4264382 0.87 LPAR3 (0.46) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL4264879 0.86 LPAR3 (0.48) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL4275598 0.86 LPAR3 (0.48) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL4267249 0.81 LPAR3 (0.42) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL6936352 0.75 SMN1; SMN2 (0.47) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL18866761 0.73 MEN1 (0.37) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL6935672 0.73 MEN1 (0.50) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL4273613 0.73 LPAR2 (0.39) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL23928727 0.73 ALOX15 (0.46) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183746-A1 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2023-06-15 US claimed
EP-4022058-A2 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2022-07-06 EP claimed
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2025-11-18 US disclosed
US-20230183746-A1 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2023-06-15 US disclosed
EP-4143316-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2023-03-08 EP disclosed
US-20220370635-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY SIXFOLD BIOSCIENCE LTD (GB) 2022-11-24 US disclosed
EP-4022058-A2 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2022-07-06 EP disclosed
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2022-06-14 US disclosed
WO-2021220053-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-11-04 WO disclosed
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN ALOX15 2891/4885MEN1 890/4885CYP1A2 4848/4885
US-20220370635-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY NCL, NSUN3, POLN ALOX15 2891/4885MEN1 890/4885CYP1A2 4848/4885
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY NCL, NSUN3, POLN ALOX15 2891/4885MEN1 890/4885CYP1A2 4848/4885
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN ALOX15 2891/4885MEN1 890/4885CYP1A2 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.