Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275598 | 1.00 | LPAR3 (0.48) | LPAR3LPAR2LPAR1MEN1CYP1A2 | |
| SCHEMBL4264382 | 0.98 | LPAR3 (0.46) | LPAR3LPAR2LPAR1MEN1CYP1A2 | |
| SCHEMBL4267249 | 0.93 | LPAR3 (0.42) | LPAR3LPAR2LPAR1MEN1CYP1A2 | |
| SCHEMBL23928730 | 0.86 | ALOX15 (0.41) | LPAR3LPAR2LPAR1MEN1CYP1A2 | |
| SCHEMBL4273613 | 0.85 | LPAR2 (0.39) | LPAR3LPAR2LPAR1MEN1CYP1A2 | |
| SCHEMBL29904263 | 0.80 | ALOX15 (0.39) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL19926726 | 0.78 | LPAR3 (0.52) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL6514099 | 0.78 | LPAR3 (0.52) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL19927107 | 0.78 | LPAR3 (0.52) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL6935672 | 0.77 | MEN1 (0.50) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| US-5939078-A | TREATING WRINKLES BY ADMINISTERING TO THE SKIN A GUANIDINE DERIVATIVE | KAO CORPORATION (JP) | 1999-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | LPAR3 1270/4885LPAR2 1765/4885LPAR1 1058/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | LPAR3 4600/4885LPAR2 4756/4885LPAR1 4431/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | LPAR3 4069/4885LPAR2 4554/4885LPAR1 3842/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | LPAR3 1947/4885LPAR2 1974/4885LPAR1 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.