SCHEMBL23928974

SCHEMBL23928974

CC(C)(C)OC(=O)N1CCC(c2nccnc2OCc2ccc(Cl)cc2F)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.46
FNTB P49356 2/20 0.46
CNR1 P21554 2/20 0.44
USP30 Q70CQ3 1/20 0.44
GPR119 Q8TDV5 3/20 0.44
DPP4 P27487 1/20 0.43
CYP3A4 P08684 2/20 0.43
CYP3A5 P20815 2/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
USP2 O75604 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
TP53 P04637 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30583912 0.88 DPP4 (0.45) FNTAFNTBCNR1USP30GPR119
SCHEMBL23928943 0.88 FNTA (0.48) FNTAFNTBUSP30GPR119DPP4
SCHEMBL23235750 0.87 KDM5A (0.43)
SCHEMBL31670786 0.86 GLP1R (0.46) CNR1USP30DPP4CYP3A4CYP3A5
SCHEMBL24320996 0.85 GLP1R (0.53) CNR1USP30GPR119DPP4CYP3A4
SCHEMBL24321002 0.84 GPR119 (0.46) CNR1USP30GPR119DPP4CYP3A4
Acetic Acid SCHEMBL28911106 0.82 GLP1R (0.42)
SCHEMBL28545272 0.82 KCNH2 (0.41)
SCHEMBL22391791 0.82 TRPV3 (0.47) CNR1USP30GPR119CYP3A4CYP3A5
SCHEMBL30209321 0.82 TRPV3 (0.47) CNR1USP30GPR119CYP3A4CYP3A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270196-A1 GLP-1 Receptor Agonists and Uses Thereof PFIZER INC. (US) 2025-08-28 US disclosed
US-12331041-B2 GLP-1 receptor agonists and uses thereof PFIZER INC. (US) 2025-06-17 US disclosed
US-20240132483-A1 GLP-1 Receptor Agonists and Uses Thereof PFIZER INC. (US) 2024-04-25 US disclosed
US-11858916-B2 GLP-1 receptor agonists and uses thereof PFIZER INC. (US) 2024-01-02 US disclosed
EP-3806855-B1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF PFIZER (US) 2023-03-01 EP disclosed
US-20210332034-A1 GLP-1 Receptor Agonists and Uses Thereof PFIZER INC. (US) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12331041-B2 GLP-1 receptor agonists and uses thereof GLP1R, GIPR, GCGR FNTA 3648/4885FNTB 3558/4885CNR1 616/4885
US-11858916-B2 GLP-1 receptor agonists and uses thereof GLP1R, GIPR, GCGR FNTA 3648/4885FNTB 3558/4885CNR1 616/4885
US-20240132483-A1 GLP-1 Receptor Agonists and Uses Thereof GLP1R, GIPR, GCGR FNTA 3648/4885FNTB 3558/4885CNR1 616/4885
US-20210332034-A1 GLP-1 Receptor Agonists and Uses Thereof GLP1R, GIPR, GCGR FNTA 3648/4885FNTB 3558/4885CNR1 616/4885
US-20250270196-A1 GLP-1 Receptor Agonists and Uses Thereof GLP1R, GIPR, GCGR FNTA 3648/4885FNTB 3558/4885CNR1 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.