Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929224 | 0.75 | KCNH2 (0.44) | KCNH2BACE1DAOESR1ESR2 | |
| SCHEMBL13495125 | 0.74 | L3MBTL1 (0.47) | KCNH2BACE1DAOESR1ESR2 | |
| SCHEMBL64650 | 0.74 | BACE1 (0.49) | KCNH2BACE1DAOESR1ESR2 | |
| SCHEMBL17672395 | 0.73 | HCAR2 (0.60) | KCNH2DAOHCAR3HCAR2 | |
| SCHEMBL27768180 | 0.72 | RAB9A (0.52) | KCNH2BACE1DAOESR1ESR2 | |
| SCHEMBL14719095 | 0.72 | DAO (0.55) | KCNH2BACE1DAOPARP1HCAR2 | |
| SCHEMBL15964734 | 0.71 | HCAR3 (0.47) | KCNH2BACE1DAOAURKALMNA | |
| SCHEMBL28809834 | 0.70 | AKR1B1 (0.50) | KCNH2BACE1DAOMAOBPARP1 | |
| SCHEMBL24622014 | 0.70 | KCNH2 (0.43) | KCNH2BACE1DAOESR1ESR2 | |
| SCHEMBL6367872 | 0.70 | TP53 (0.43) | KCNH2BACE1DAOESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139275-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Syneurx International (Taiwan) Corp. (TW) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021213500-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2021-10-28 | — | — | WO | disclosed |