Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23960911 | 0.86 | KMT2A (0.61) | KMT2AALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL6565018 | 0.86 | RAB9A (0.62) | KMT2AALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL12301999 | 0.78 | CYP3A4 (0.60) | KMT2AALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL22501097 | 0.77 | MAPT (0.65) | KMT2AALDH1A1SMN1; SMN2MEN1MAPK1 | |
| SCHEMBL31356929 | 0.75 | ALDH1A1 (0.74) | KMT2AALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL12302133 | 0.75 | ALDH1A1 (0.74) | KMT2AALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL22501273 | 0.74 | KMT2A (0.77) | KMT2AALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL30964136 | 0.74 | KMT2A (0.77) | KMT2AALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL6749335 | 0.74 | ALDH1A1 (0.65) | KMT2AALDH1A1HSD17B10L3MBTL1MEN1 | |
| SCHEMBL2627764 | 0.74 | ALDH1A1 (0.68) | KMT2AALDH1A1TSHRSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874361-A | Novel compound with anticancer activity and preparation method thereof | 医药生命融合研究团 | 2021-12-31 | — | — | CN | claimed |
| CN-113874361-B | Compound with anticancer activity and preparation method thereof | 医药生命融合研究团 | 2024-07-12 | — | — | CN | disclosed |
| CN-115867537-A | Improved process for the preparation of a rasagiline base | 迈兰实验室有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113874361-A | Novel compound with anticancer activity and preparation method thereof | 医药生命融合研究团 | 2021-12-31 | — | — | CN | disclosed |
| WO-2021214785-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ROXADUSTAT | MYLAN LABORATORIES LIMITED (IN) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021214785-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ROXADUSTAT | MYLAN LABORATORIES LIMITED (IN) | 2021-10-28 | — | — | WO | disclosed |