Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929407 | 0.86 | KMT2A (0.65) | NPC1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL6565034 | 0.83 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL23014288 | 0.78 | PKM (0.55) | NPC1SMN1; SMN2POLBKMT2ALMNA | |
| SCHEMBL14335466 | 0.77 | SMN1; SMN2 (0.63) | RAB9ASMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL3362277 | 0.76 | KMT2A (0.56) | NPC1POLBKMT2ALMNAMEN1 | |
| SCHEMBL3719058 | 0.74 | PKM (0.69) | POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL359770 | 0.72 | MMP1 (0.79) | KMT2AGAAALDH1A1 | |
| SCHEMBL23960911 | 0.72 | KMT2A (0.61) | SMN1; SMN2KMT2ALMNAMEN1GAA | |
| SCHEMBL22500256 | 0.72 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2POLBLMNAALDH1A1 | |
| SCHEMBL2760714 | 0.72 | MMP1 (0.61) | SMN1; SMN2LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443041-A1 | 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |