Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26172965 | 1.00 | THRB (0.50) | THRBCNR2CNR1KCNH2MAPT | |
| SCHEMBL26172963 | 0.87 | KCNH2 (0.53) | THRBCNR2CNR1KCNH2MAPT | |
| SCHEMBL27813705 | 0.84 | CNR2 (0.55) | THRBCNR2CNR1KCNH2MAPT | |
| SCHEMBL26172960 | 0.81 | THRB (0.44) | THRBCNR2CNR1KCNH2MAPT | |
| SCHEMBL25811431 | 0.80 | THRB (0.53) | THRBKCNH2MAPTL3MBTL1MEN1 | |
| SCHEMBL23964328 | 0.78 | THRB (0.61) | THRBMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL27792385 | 0.77 | ALDH1A1 (0.57) | THRBKCNH2MAPTL3MBTL1MEN1 | |
| SCHEMBL10803651 | 0.76 | TGM2 (0.46) | THRBKCNH2 | |
| SCHEMBL23964326 | 0.75 | MAP1LC3B (0.44) | THRBMAPTKMT2ALMNAMAPK1 | |
| SCHEMBL25808301 | 0.75 | THRB (0.57) | THRBMAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213518-A1 | COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES | 复旦大学 (CN) | 2021-10-28 | — | — | WO | disclosed |