SCHEMBL23930713

SCHEMBL23930713

N#CC1COCc2cnccc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.32
AAK1 Q2M2I8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300098 0.76 NOTUM (0.32)
SCHEMBL23022285 0.75 SIGMAR1 (0.34) SIGMAR1
SCHEMBL24742538 0.71 AAK1 (0.32) SIGMAR1AAK1
SCHEMBL23704762 0.68 HTR2A (0.33)
SCHEMBL4463156 0.66 CHRNB2 (0.33) SIGMAR1AAK1
SCHEMBL31618365 0.65 CHRNB2 (0.38) SIGMAR1
SCHEMBL31618283 0.65 CHRNB2 (0.35) SIGMAR1
SCHEMBL19839218 0.65 CHRNB2 (0.49) SIGMAR1
SCHEMBL147460 0.64
SCHEMBL6871401 0.62 CHRNB2 (0.36) SIGMAR1AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021215765-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 주식회사 엘지화학 (KR) 2021-10-28 WO disclosed