Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23022285 | 0.69 | SIGMAR1 (0.34) | CHRNB2CHRNA4SIGMAR1 | |
| SCHEMBL6871401 | 0.67 | CHRNB2 (0.36) | CHRNB2CHRNA4SIGMAR1AAK1 | |
| SCHEMBL9841996 | 0.66 | SIGMAR1 (0.38) | CHRNB2CHRNA4SIGMAR1AAK1 | |
| SCHEMBL23930713 | 0.66 | SIGMAR1 (0.32) | SIGMAR1AAK1 | |
| SCHEMBL24742538 | 0.66 | AAK1 (0.32) | SIGMAR1AAK1 | |
| SCHEMBL31618365 | 0.66 | CHRNB2 (0.38) | CHRNB2CHRNA4SIGMAR1RPS6KA3CHRNA7 | |
| SCHEMBL147460 | 0.65 | — | — | |
| SCHEMBL19372741 | 0.62 | CHRNB2 (0.33) | CHRNB2CHRNA4RPS6KA3CHRNA7 | |
| SCHEMBL15386162 | 0.62 | IDO1 (0.43) | CHRNB2CHRNA4SIGMAR1CHRNA7DRD2 | |
| SCHEMBL9842267 | 0.62 | SIGMAR1 (0.38) | CHRNB2CHRNA4SIGMAR1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495101-B2 | Manufacture of vitamin B6 | DSM IP ASSETS B.V. (NL) | 2009-02-24 | — | — | US | disclosed |
| US-20070072254-A1 | Manufacture of vitamin b6 | DSM IP ASSETS B.V. (NL) | 2007-03-29 | — | — | US | disclosed |